A Certificate of Analysis (COA) is your most important tool for verifying peptide quality before purchase. This practical checklist will help you evaluate COAs like a professional, ensuring you receive genuine, high-quality research peptides.
What Is a COA?
A COA is an official document provided by the manufacturer that certifies the identity, purity, and quality of a specific batch of peptide. It should contain analytical data from validated testing methods.
Essential COA Checklist
- Peptide Identity: Confirm the amino acid sequence matches your order exactly
- Molecular Weight: Verify the measured molecular weight matches the theoretical value (typically via Mass Spectrometry)
- Purity Percentage: Check HPLC purity — ≥95% for general research, ≥98% for critical applications
- Batch/Lot Number: Ensure a unique batch number is present for traceability
- Manufacturing Date: Peptides degrade over time; verify the product is not expired
- Storage Conditions: Confirm recommended storage temperature (typically -20°C)
- Test Methods: Look for HPLC and MS data — these are the gold standard for peptide analysis
- Appearance Description: Physical description should match the product (color, form)
- Solubility Information: Guidance on recommended solvents and concentrations
Warning: A COA that lacks HPLC chromatograms or MS spectra is a major red flag. Reputable suppliers always include raw analytical data, not just summary numbers.
Common COA Issues
- Missing analytical data: No HPLC or MS data provided
- Copy-paste COAs: The same COA used for different batches or products
- Outdated information: COA dates that don't match the manufacturing timeline
- No batch traceability: Cannot link the COA to the specific product you received
PeptideCHN COA Standards
Every PeptideCHN product ships with a comprehensive COA including full HPLC chromatograms, MS spectra, purity data, batch traceability, and storage recommendations. We believe in complete transparency because your research depends on it.
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